Searchable abstracts of presentations at key conferences in endocrinology

ea0056s4.1 | Environmental effects on endocrine functions | ECE2018

Developmental exposures to endocrine disrupting chemicals (EDCs) reprogram the epigenome to increase risk for hormone-dependent cancers and other diseases of adilthood

Walker Cheryl

While organisms have evolved to maintain the fidelity of their genome, the epigenome, in contrast, is inherently plastic, with extensive remodeling required during normal development. This epigenomic plasticity plays a role in preparing the developing organism for its adult environment. The epigenome is able to sense environmental cues, providing an opportunity for adaptive changes during development that can provide a later-life survival advantage. However, epigenomic plastic...